Nasal Polyps New Treatment

In recent study, an increased expression of GRb mRNA was found in epithelial cell extracts from nasal polyps compared to nasal mucosa, which was more evident in those polyp samples containing more than 3% of inflammatory cells. The higher expression of GRb in nasal polyps apparently accounts for the inflammatory cells that remained after panning, for a correlation was found between GRb expression and the number of inflammatory cells, especially mast cells, present in the epithelial cell extracts.  This study is tempted to speculate that if we had not removed the inflammatory cell content from nasal polyps, it would probably have found a more marked difference in the expression of GRb mRNA in nasal polyps with respect to nasal mucosa. Indeed, Hamilos and coworkers have recently reported that GRb expression in nasal polyps is confined to inflammatory cells, particularly T lymphocytes, eosinophils, and macrophages.The authors also reported increased number of GRb-positive inflammatory...